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Total iron-binding capacity : ウィキペディア英語版
Total iron-binding capacity

Total iron-binding capacity (TIBC) or sometimes transferrin iron-binding capacity is a medical laboratory test that measures the blood's capacity to bind iron with transferrin.〔(【引用サイトリンク】title=MedlinePlus Medical Encyclopedia: Total iron binding capacity )〕 It is performed by drawing blood and measuring the maximum amount of iron that it can carry, which indirectly measures transferrin since transferrin is the most dynamic carrier. TIBC is less expensive than a direct measurement of transferrin.
The TIBC should not be confused with the UIBC, or "unsaturated iron binding capacity" ( and ). The UIBC is calculated by subtracting the serum iron from the TIBC.〔(【引用サイトリンク】title=Iron Transport )
==Interpretation==
Taken together with serum iron and percent transferrin saturation clinicians usually perform this test when they are concerned about anemia, iron deficiency or iron deficiency anemia. However, because the liver produces transferrin, alterations in function (such as cirrhosis, hepatitis, or liver failure) must be considered when performing this test. It can also be an indirect test of liver function, but is rarely used for this purpose.
The percent transferrin saturation (i.e., the result of the formula of serum iron/TIBC x 100) can also be a useful indicator.
These examples demonstrate that to properly understand a value for TIBC, one also must know the serum iron, the percent transferrin saturation, and the individual clinical situation. In modern laboratory testings, serum ferritin levels are generally accepted as reliable single indicators of the presence of iron deficiency.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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